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Shephard Mpofu Selected Research

secukinumab

1/2021Secukinumab provides sustained improvement in signs and symptoms and low radiographic progression in patients with psoriatic arthritis: 2-year (end-of-study) results from the FUTURE 5 study.
1/2021Secukinumab Efficacy on Enthesitis in Patients With Ankylosing Spondylitis: Pooled Analysis of Four Pivotal Phase III Studies.
1/2020Secukinumab provides sustained low rates of radiographic progression in psoriatic arthritis: 52-week results from a phase 3 study, FUTURE 5.
1/2020Secukinumab versus adalimumab for treatment of active psoriatic arthritis (EXCEED): a double-blind, parallel-group, randomised, active-controlled, phase 3b trial.
1/2020Secukinumab Provides Sustained Improvements in the Signs and Symptoms of Psoriatic Arthritis: Final 5-year Results from the Phase 3 FUTURE 1 Study.
12/2018Correction to: Secukinumab Versus Adalimumab for Psoriatic Arthritis: Comparative Effectiveness up to 48 Weeks Using a Matching-Adjusted Indirect Comparison.
10/2018Minimal Disease Activity Among Active Psoriatic Arthritis Patients Treated With Secukinumab: 2-Year Results From a Multicenter, Randomized, Double-Blind, Parallel-Group, Placebo-Controlled Phase III Study.
6/2018Secukinumab Versus Adalimumab for Psoriatic Arthritis: Comparative Effectiveness up to 48 Weeks Using a Matching-Adjusted Indirect Comparison.
1/2018Secukinumab in the treatment of psoriatic arthritis: efficacy and safety results through 3 years from the year 1 extension of the randomised phase III FUTURE 1 trial.
1/2018Efficacy and safety of secukinumab administration by autoinjector in patients with psoriatic arthritis: results from a randomized, placebo-controlled trial (FUTURE 3).
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Shephard Mpofu Research Topics

Disease

18Psoriatic Arthritis
01/2021 - 08/2015
6Infections
01/2020 - 06/2013
4Psoriasis (Pustulosis Palmaris et Plantaris)
06/2018 - 08/2015
3Ankylosing Spondylitis
01/2021 - 12/2015
3Candidiasis (Moniliasis)
01/2020 - 12/2015
3Crohn Disease (Crohn's Disease)
01/2020 - 12/2015
3Rheumatoid Arthritis
03/2014 - 06/2013
2Cardiovascular Diseases (Cardiovascular Disease)
01/2020 - 01/2018
2Body Weight (Weight, Body)
06/2018 - 12/2015
2Disease Progression
01/2018 - 01/2017
2Chronic Disease (Chronic Diseases)
01/2017 - 03/2014
2Fatigue
01/2017 - 03/2014
1Colonic Neoplasms (Colon Cancer)
01/2020
1Ulcerative Colitis
01/2018
1Necrosis
01/2018
1Pain (Aches)
01/2017
1Neutropenia
12/2015
1Stroke (Strokes)
10/2015
1Myocardial Infarction
10/2015
1Respiratory Tract Infections (Respiratory Tract Infection)
09/2015
1Nasopharyngitis
09/2015

Drug/Important Bio-Agent (IBA)

24secukinumabIBA
01/2021 - 06/2013
6Interleukin-17 (Interleukin 17)IBA
01/2018 - 09/2015
3Adalimumab (Humira)FDA Link
01/2020 - 06/2018
3Monoclonal AntibodiesIBA
12/2015 - 08/2015
1Methotrexate (Mexate)FDA LinkGeneric
06/2018
1amsonic acid (DAS)IBA
11/2017
1Tumor Necrosis Factor InhibitorsIBA
01/2016
1CytokinesIBA
09/2015
1Etanercept (Enbrel)FDA Link
08/2015
1ametantrone (HAQ)IBA
03/2014

Therapy/Procedure

4Therapeutics
06/2018 - 03/2014
1Self Administration (Administration, Self)
01/2018